To address the issues of voltage mismatch, limited power extraction, and regulation losses in triple-well on-chip solar cells, this work implements a storage-free dual-channel EH system in standard 0.18-μ m CMOS technology. The system employs a per-port independent boosting architecture with post-boost parallel merging, effectively avoiding energy losses caused by MPP voltage mismatch in conventional designs. Meanwhile, a voltage regulation mechanism based on the load characteristics of the solar cell achieves stabilization without an LDO, enabling fast power control and adaptive power distribution, which better suits the requirements of storage-free EH. Experimental results show that the system maintains a stable 1.22-V output under varying illumination and load conditions; compared with a single-channel design, the voltage ripple is reduced from 102 to 21 mV, the load capacity is improved by 6.31%, and peak circuit and system efficiencies of 63.97% and 9.63% are achieved at 100 kLux, respectively. These results verify the proposed dual-channel EH system’s optimization in power extraction and voltage regulation, highlighting its potential for self-powered microsystems and hybrid energy architectures.